Assessing splenic vein complications in patients with acute pancreatitis using color Doppler ultrasound and contrast enhanced ultrasound.AbstractOBJECTIVE: To evaluate the diagnostic value of color Doppler flow imaging （CDFI） and contrast enhanced ultrasonography （CEUS） for splenic vein complications （SVCs）. METHODS: 144 inpatients （86 male, 58 female） with acute pancreatitis from Jan 2012 to Apr 2013 were recruited for this study. The participants had a mean age of （44.3 +/- 11.9） years. All participants were examined using CDFI, CEUS and contrast enhanced computer tomography （CECT） （less than 72 h interval between examinations）. The CECT results were regarded as a golden standard, which were compared with the results of CDFI and CEU. The Medcalc 12.7.1.0 was used for drawing ROC curves and calculating AUC. RESULTS: The CECT confirmed 17 cases of SVCs; whereas, the CEUS identified 12 cases and the CDFI identified 4 cases of SVCs. The difference between the results of CDFI and CEUS was significant （Z = 2.233, P < 0.05）. Higher levels of sensitivity （58.82%）, specificity （98.43%）, accuracy （93.75%）, positive likelihood ratio （37.46）, and negative likelihood ratio （0. 42） were found using CEUS for diagnosing SVCs, compared with those of using CDFI （sensitivity = 17.65%, specificity = 99.21%, accuracy = 89.58%, positive likelihood ratio = 22.34,negative likelihood ratio = 0.83）. The area of AUC were 0.618 and 0.853 for CDFI and CEUS, respectively. CONCLUSION: CEUS is a better imaging method for diagnosing SVCs in patients with acute pancreatitis. Sichuan Da Xue Xue Bao Yi Xue Ban. 2014 Sep;45（5）:850-3. PMID: 25341353 [PubMed - in process]
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