武汉同济医院李小明 Ankylosing spondylitis: correlations between clinical and MRI indices of sacroiliitis activity.

Clin Radiol. 2015 Jan;70（1）:62-6. doi: 10.1016/j.crad.2014.09.015. Epub 2014 Oct 22.

Ankylosing spondylitis: correlations between clinical and MRI indices of sacroiliitis activity.

Zhang P¹, Yu K², Guo R¹, Shah S¹, Morelli JN³, Runge VA⁴, Li X⁵.

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Abstract

AIM:

To analyse the correlations between clinical and MRI sacroiliitis activity indices in ankylosing spondylitis （AS）.

MATERIALS AND METHODS:

Sixteen normal volunteers and 52 patients were enrolled. The clinical AS activity indices included the BathAnkylosing Spondylitis Disease Activity Index （BASDAI） score, serum high-sensitivity C-reactive protein, and erythrocyte sedimentation rate. TheMRI sacroiliitis activity indices included apparent diffusion coefficient （ADC） values of bone and the Spondyloarthritis Research Consortium of Canada （SPARCC） score.

RESULTS:

The mean SPARCC score of the control group was 0 and of the AS group was 9.9 ± 9.1 （range 0-36）. The mean ADC value of the AS group was statistically significantly higher than that of the control group （49.7 ± 20.2 × 10（-5）mm（2）/s versus 38.9 ± 5.3 × 10（-5）mm（2）/s, p < 0.05）. The BASDAI score showed a statistically significant correlation with the SPARCC score （r = 0.685, p < 0.05） and with ADC values （r = 0.329, p < 0.05）. ADC values correlated with the SPARCC score （r = 0.390, p < 0.05）.

CONCLUSION:

ADC values and the SPARCC index may be useful activity indices in AS.

Copyright © 2014 The Royal College of Radiologists. All rights reserved.

PMID: 25459199 DOI: 10.1016/j.crad.2014.09.015 [PubMed - indexed for MEDLINE]