华西医院刘荣波 Unicentric mesenteric Castleman& #39;s disease with littoral cell angioma, anemia, growth retardation and amenorrhea: A case report.

Oncol Lett. 2015 Apr;9（4）:1779-1781. Epub 2015 Feb 5.

Unicentric mesenteric Castleman's disease with littoral cell angioma, anemia, growth retardation and amenorrhea: A case report.

Yang L¹, Zhao S¹, Liu RB¹.

Author information

• ¹Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610000, P.R. China.

Abstract

Castleman's disease （CD） is a rare lymphoproliferative disorder of unknown origin, and littoral cell angioma （LCA） is a rare vascular tumor of the spleen with an unknown etiology. The current study reports the case of a 28-year-old female who presented with anemia, growth retardation and amenorrhea. Physical examination revealed a mass in the mesentery, splenomegaly with multiple small nodules, hepatomegaly and an infantile uterus. Histopathological analysis of the resected mass and spleen confirmed the diagnosis of hyaline-vascular CD and LCA. The patient's anemia resolved, and menstruation and breast development also commenced following surgery. To the best of our knowledge, this is the first report of CD accompanied by littoral cell angioma, anemia, growth retardation and amenorrhea.

KEYWORDS:

Castleman's disease; anemia; computed tomography; growth retardation; littoral cell angioma

PMID: 25789041 [PubMed] PMCID: PMC4356425