Isolated non-compaction of ventricular myocardium in a victim of the Wenchuan earthquake with crush syndrome and acute renal failure.1Division of Nephrology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
AbstractNon—compaction of the ventricular myocardium （NVM） is a rare congenital genetic heart defect that was initially reported 17 years ago by means of autopsy；few cases have been published since then．It has been classified as the primary inherited cardiomyopathy by the American Heart Association Scientific Statement in 2006 under contemporary definitions and classification of cardiomyopathies. It is caused by an arrested development of muscle fiber compaction，a process that normally takes place during early embryogenesis，which is characterized by numerous sinusoids or trabeculae that are excessive in number and abnormal in prominence and by deep intratrabecular recesses covered by endothelium that exhibits continuity with ventricular endocardium．It usually involves one and／or more segments of the left Ventricle, while the clinical manifestations are highly variable，ranging from asymptomatic to congestive heart failure，arrhythmias，systemic embolic events，and sudden cardiac death. The most frequent symptom is heart failure, mainly of the left ventficular origin． Chin Med J （Engl）. 2009 Sep 20;122（18）:2196-8. PMID: 19781312 [PubMed - indexed for MEDLINE]
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